4.6 (765) In stock
Surgical resection is an important avenue for cancer treatment, which, in most cases, can effectively alleviate the patient symptoms. However, accumulating evidence has documented that surgical resection potentially enhances metastatic seeding of tumor cells. In this review, we revisit the literature on surgical stress, and outline the mechanisms by which surgical stress, including ischemia/reperfusion injury, activation of sympathetic nervous system, inflammation, systemically hypercoagulable state, immune suppression and effects of anesthetic agents, promotes tumor metastasis. We also propose preventive strategies or resolution of tumor metastasis caused by surgical stress.
Frontiers Laparoscopic Versus Open Surgery for Early-Stage
Surgical Stress and Cancer Progression: New Findings and Future
Biodegradable electrospun nanofibrous platform integrating
JMP, Free Full-Text
Thorny ground, rocky soil: Tissue-specific mechanisms of tumor
New insights into the correlations between circulating tumor cells
Pharmaceuticals, Free Full-Text
Frontiers Perioperative Inflammatory Response and Cancer
A case of disseminated carcinomatosis of the bone marrow from
Effects of dexmedetomidine on A549 non-small cell lung cancer
Pharmaceutics, Free Full-Text
Frontiers Perioperative oncolytic virotherapy to counteract
Stresses in the metastatic cascade: molecular mechanisms and
